Nature Metabolism
This journal publishes work from across all fields of metabolism research that significantly advances our understanding of metabolic and homeostatic processes in a cellular or broader physiological context, from fundamental cell biology to basic biomedical and translational research.
Procyanidin C1 is a natural agent with senolytic activity against ageing and age-related diseases
Advancements of studies with model organisms that cellular senescence drives ageing and age-related pathologies have elicited widespread efforts to identify compounds of a potential to selectively kill senescent cells, now termed as 'senolytics'.
Fasting is required for the benefits of calorie restriction: The importance of when we eat
Restricting calorie intake extend lifespan and healthspan of many species, but the mechanism of how calorie restriction functions remains unclear. We show that prolonged fasting between meals imposed by such regimens may play a critical role in the benefits of reduced calorie diets.