The rapid evolution of chemical and bioanalytical sciences is driven by micro and nanomaterials whose performance is governed by engineered interfaces. At the nanoscale, surface chemistry controls molecular recognition, signal transduction, sensitivity, and selectivity, enabling analytical capabilities beyond those of conventional materials. Nano-enabled interfaces based on quantum dots, nanozymes, molecular frameworks, mesoporous structures, thin films, and hybrid materials are central to advanced chemical and biosensing platforms. Recent advances in interface functionalization and bio-recognition have enabled sensitive sensing for point-of-care diagnostics, environmental analysis, and biomedical applications. This Topical Collection focuses on original research articles reporting innovative nano-interface-based analytical methods and sensing devices, emphasizing interface-driven signal amplification and real-world analytical applicability.

The growing emphasis on environmental and human health has led to sustainable practices in analytical chemistry. In the realm of Green and White Analytical Chemistry (GAC-WAC), a diverse array of eco-friendly micro- and nanomaterials has been developed, aligning with key principles of green chemistry and high analytical performance. These eco-friendly materials are distinguished by their sustainability and low environmental impact. They reflect a paradigm shift toward greener, cleaner and ethically sound analytical approaches, with applications in diverse fields.

This topical collection focuses on conceptualization, synthesis and applications of eco-friendly micro- and nanomaterials and functional composites that address the dual challenge of achieving high analytical performance while minimizing environmental footprint, thereby contributing towards sustainable analytical workflow. It seeks to bridge the gap between green material science and analytical innovations by promoting the engineering of materials/composites that deliver high analytical performance while ensuring safety, resource efficiency and sustainability. Contributions, reflecting a system-level understanding of analytical outcomes influenced by micro- and nanomaterials in line with GAC and WAC paradigms, are highly encouraged.