Integrative Mitochondrial Medicine; Adipose Tissue: From Cellular Mechanisms to Systemic Health; Incretin Biology and Therapeutics: Transforming Obesity and Associated Diseases
Published in Cancer, Genetics & Genomics, and General & Internal Medicine
Integrative Mitochondrial Medicine
March 21 - 24, 2027 @ Fairmont Banff Springs, Banff, AB, Canada
Important Deadlines
Early Registration Deadline: January 19, 2027
Scholarship Deadline: December 1, 2026
Short Talk Abstract Deadline: December 1, 2026
Poster Abstract Deadline: March 1, 2027
Meeting Summary
Title: Integrative Mitochondrial Medicine
Date: March 21 - 24, 2027
Location: Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers: Nils-Goran Larsson and Aleksandra Filipovska
Keynote Speaker(s): Vamsi K. Mootha, Massachusetts General Hospital
Mitochondrial biology is central to cellular health, as its dysfunction is implicated in cancer, neurodegeneration, and metabolic diseases. New therapeutic innovations in leveraging medicinal synthetic biology, including genome editing and small molecules, are key to targeting mitochondrial dysfunction and overcoming bioenergetic challenges. A major gap remains in understanding how mitochondria communicate with other organelles within cells and tissues—a challenge that can be addressed by integrating lipid and metabolic flux analyses (fluxomics) with high-resolution 3D imaging techniques, including volumetric electron microscopy.
The upcoming Keystone meeting 'Integrative Mitochondrial Medicine' aims to bridge cell and structural biology with dynamic metabolite profiling and bioenergetics. Sessions will explore mitochondrial genome and transcriptome editing and synthetic biology platforms to understand or enhance organelle crosstalk and reprogram metabolic pathways, advancing the field toward novel biomarkers and standardized protocols for multi-scale mitochondrial analyses. It will showcase cutting-edge technologies like cryo-electron tomography and AI-driven morphometric quantitation to resolve mitochondrial ultrastructure in health and disease.
This meeting stands out by uniting cell biologists, clinicians, computational modelers, and bioengineers. Unique workshops will pair structural imaging experts with fluxomics specialists to decode spatial-metabolic relationships, while panels foster dialogue between synthetic biologists and pharmaceutical researchers on drugging mitochondrial targets. Innovative program elements include hands-on virtual reality platforms for 3D reconstruction and a 'Shark Tank'-style session for pitching therapeutic concepts to investors. Attendees and editors will have the opportunity to sample emerging trends in integrative mitochondrial approaches, positioning this forum as a nexus for next-generation mitochondrial medicine and clinical translation.
Join Options
Attend in person, via livestream, or catch sessions on demand after the conclusion of the conference.
*Keystone Symposia Scholarships & Awards*
Keystone Symposia offers discounted registration to students in undergraduate, M.S., Ph.D., or M.D. programs, providing access to the latest scientific advances, technologies, and approaches to further research and careers.
In addition, several financial aid opportunities are also available to support attendance at its scientific meetings:
- Student and Postdoctoral Scholarships provide up to $1,200 to help defray travel, lodging, registration, and related costs when presenting a poster at an in-person conference. Awards are competitive, based on the abstract’s scientific quality and relevance, and you must apply by the individual scholarship deadline for the desired meeting (abstract + mentor letter required).
- Early-Career Travel Awards (ECITAs) support early-career investigators with funding to attend meetings; these also require application by the posted deadline for each conference.
- Global Health Travel Awards (GHTAs) provide financial aid for scientists, clinicians, fellows, and students from low- and middle-income countries (LMICs) to participate in select Keystone Symposia meetings, especially those focused on global health topics. These awards may cover registration, lodging, airfare, and ground transportation, and applications are submitted through the Financial Aid Portal by the listed meeting deadlines. Learn which meetings have in-person GHTAs available: https://www.keystonesymposia.org/financial-aid/global-health-awards/ghta-listing
For details on eligibility, deadlines, and how to apply for financial aid, visit: https://www.keystonesymposia.org/financial-aid.
Adipose Tissue: From Cellular Mechanisms to Systemic Health
March 21 - 24, 2027 @ Fairmont Banff Springs, Banff, AB, Canada
Important Deadlines
Early Registration Deadline: January 20, 2027
Scholarship Deadline: December 2, 2026
Short Talk Abstract Deadline: December 2, 2026
Poster Abstract Deadline: March 2, 2027
Meeting Summary
Title: Adipose Tissue: From Cellular Mechanisms to Systemic Health
Date: March 21 - 24, 2027
Location: Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers: Kirsty L. Spalding, Camilla C Schéele, and Clair Crewe
Keynote Speaker(s): Daniel J. Drucker, Lunenfeld-Tanenbaum Research Institute and Philipp E. Scherer, University of Texas Southwestern Medical Center
Once considered a passive reservoir for energy storage, adipose tissue is now recognized as a dynamic organ with wide-ranging effects on systemic physiology. In health, it regulates metabolism, thermogenesis, immune defense, and endocrine communication. In disease, excess or dysfunction of adipose tissue contributes to obesity, metabolic disorders, cardiovascular disease, and cancer.
This Keystone Symposium will highlight cutting-edge advances in adipose biology, spanning fundamental mechanisms to translational applications. Key themes include:
- Adipose-Incretin Interactions: Exploring how incretin biology intersects with adipose tissue function and therapeutic targeting.
- Extracellular Communication: Defining the role of adipose-derived vesicles, RNAs, and signals as novel mediators of cardiometabolic and neuroendocrine crosstalk.
- Therapeutic Targeting: Evaluating strategies to modulate adipose tissue, from polyagonists and depot-selective interventions to ß2-agonists and next-generation therapeutics.
- Adipose Tissue and Cancer: Uncovering how adipocytes and tumour cells interact, with implications for tumour progression and therapy.
- Adipose-Immune Interactions: Dissecting how immune pathways influence adipose tissue plasticity, inflammation, and systemic metabolic outcomes.
- Evolutionary Perspectives: Leveraging comparative biology across species, from hibernating mammals to fish, to uncover fundamental principles of adipose adaptation.
Paired with the Keystone Symposium on incretin biology, this meeting will convene leaders from academia, industry, and clinical science to foster cross-disciplinary dialogue. Together, the program emphasizes how insights into adipose tissue cellularity, signaling, and plasticity can inform innovative strategies for obesity, metabolic disease, and cancer.
*This meeting will be held jointly with Incretin Biology and Therapeutics: Transforming Obesity and Associated Diseases
Join Options
Attend in person, via livestream, or catch sessions on demand after the conclusion of the conference.
*Keystone Symposia Scholarships & Awards*
Keystone Symposia offers discounted registration to students in undergraduate, M.S., Ph.D., or M.D. programs, providing access to the latest scientific advances, technologies, and approaches to further research and careers.
In addition, several financial aid opportunities are also available to support attendance at its scientific meetings:
- Student and Postdoctoral Scholarships provide up to $1,200 to help defray travel, lodging, registration, and related costs when presenting a poster at an in-person conference. Awards are competitive, based on the abstract’s scientific quality and relevance, and you must apply by the individual scholarship deadline for the desired meeting (abstract + mentor letter required).
- Early-Career Travel Awards (ECITAs) support early-career investigators with funding to attend meetings; these also require application by the posted deadline for each conference.
- Global Health Travel Awards (GHTAs) provide financial aid for scientists, clinicians, fellows, and students from low- and middle-income countries (LMICs) to participate in select Keystone Symposia meetings, especially those focused on global health topics. These awards may cover registration, lodging, airfare, and ground transportation, and applications are submitted through the Financial Aid Portal by the listed meeting deadlines. Learn which meetings have in-person GHTAs available: https://www.keystonesymposia.org/financial-aid/global-health-awards/ghta-listing
For details on eligibility, deadlines, and how to apply for financial aid, visit: https://www.keystonesymposia.org/financial-aid.
Incretin Biology and Therapeutics: Transforming Obesity and Associated Diseases
March 21 - 24, 2027 @ Fairmont Banff Springs, Banff, AB, Canada
Important Deadlines
Early Registration Deadline: January 20, 2027
Scholarship Deadline: December 2, 2026
Short Talk Abstract Deadline: December 2, 2026
Poster Abstract Deadline: March 2, 2027
Meeting Summary
Title: Incretin Biology and Therapeutics: Transforming Obesity and Associated Diseases
Date: March 21 - 24, 2027
Location: Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers: Zach Gerhart-Hines, Richard D DiMarchi, and Fiona M. Gribble
Keynote Speaker(s): Daniel J. Drucker, Lunenfeld-Tanenbaum Research Institute and Philipp E. Scherer, University of Texas Southwestern Medical Center
Decades of research and chemical innovation around the gut hormones, GLP-1 and GIP, have revolutionized the treatment of diabetes and obesity, achieving results once possible only with surgery. Despite this success, our understanding of how these molecules work remains incomplete. Moreover, their broader potential in treating other diseases, such as neurodegenerative disorders, is just beginning to emerge. Thus, in this meeting, we aim to leverage the collective expertise of basic and clinical researchers teamed with pharmaceutical scientists to discuss cutting-edge insights into incretin biology as well explore novel mechanisms and approaches that will be necessary to further propel the treatment of obesity and numerous additional disease indications.
Key themes include:
- The latest mechanistic and methodological advances in incretin biology, including the role of anti-inflammatory incretin action, dissection of central versus peripheral actions on homeostasis, and consideration of the risks and opportunities presented by deeper brain penetrance of incretin agonists
- Constructive debate over topics such as GIP agonism versus antagonism, the consequences of lean mass loss and metabolic adaptation, and quantity versus quality of weight loss
- Exploration of novel biologies and targets that could address unmet clinical needs beyond incretins, including energy expenditure and alternative mechanisms of appetite control and gut-brain signaling
- New therapeutic avenues made possible by chemical advances in small molecule agonist design, biased signaling, conjugated polyagonists, and extended drug exposure.
Anticipated Outcome:
We hope this meeting will catalyze paradigm shifts in approaches to obesity management and set a road map for the next generation of therapies that will provide transformative benefits across a spectrum of disease indications.
*This meeting will be held jointly with Adipose Tissue: From Cellular Mechanisms to Systemic Health
Join Options
Attend in person, via livestream, or catch sessions on demand after the conclusion of the conference.
*Keystone Symposia Scholarships & Awards*
Keystone Symposia offers discounted registration to students in undergraduate, M.S., Ph.D., or M.D. programs, providing access to the latest scientific advances, technologies, and approaches to further research and careers.
In addition, several financial aid opportunities are also available to support attendance at its scientific meetings:
- Student and Postdoctoral Scholarships provide up to $1,200 to help defray travel, lodging, registration, and related costs when presenting a poster at an in-person conference. Awards are competitive, based on the abstract’s scientific quality and relevance, and you must apply by the individual scholarship deadline for the desired meeting (abstract + mentor letter required).
- Early-Career Travel Awards (ECITAs) support early-career investigators with funding to attend meetings; these also require application by the posted deadline for each conference.
- Global Health Travel Awards (GHTAs) provide financial aid for scientists, clinicians, fellows, and students from low- and middle-income countries (LMICs) to participate in select Keystone Symposia meetings, especially those focused on global health topics. These awards may cover registration, lodging, airfare, and ground transportation, and applications are submitted through the Financial Aid Portal by the listed meeting deadlines. Learn which meetings have in-person GHTAs available: https://www.keystonesymposia.org/financial-aid/global-health-awards/ghta-listing
For details on eligibility, deadlines, and how to apply for financial aid, visit: https://www.keystonesymposia.org/financial-aid.
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