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Hepatocyte-targeting nanoparticles for enhanced hepatobiliary MRI

Hepatobiliary MRI can be enhanced by an ultrasmall nanoparticle composed of a manganese ferrite core and surface ligands binding to hepatocyte-specific transmembrane metal and anion transporters, as shown in small and large animals.
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Pep Pàmies
Chief Editor, Nature Biomedical Engineering, Nature Research
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Nature
Nature Nature

A hepatocyte-targeting nanoparticle for enhanced hepatobiliary magnetic resonance imaging - Nature Biomedical Engineering

Hepatobiliary MRI can be enhanced by an ultrasmall nanoparticle composed of a manganese ferrite core and surface ligands binding to hepatocyte-specific transmembrane metal and anion transporters, as shown in small and large animals.

The cover illustrates an ultrasmall nanoparticle with a manganese ferrite core and with surface ligands with high specificity for hepatocytes, for use as a contrast agent for imaging the liver and the biliary tree.

See Zhang et al.

Image: Haiming Fan, Northwest University. Cover design: Allen Beattie.
Go to the profile of Pep Pàmies
Pep Pàmies
Chief Editor, Nature Biomedical Engineering, Nature Research

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Biotechnology
Life Sciences > Biological Sciences > Biotechnology

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