Nature Biomedical Engineering
This journal aspires to become the most prominent publishing venue in biomedical engineering by bringing together the most important advances in the discipline, enhancing their visibility, and providing overviews of the state of the art in each field.
Antibody-displaying extracellular vesicles for targeted cancer therapy
Extracellular vesicles (EVs) function as natural delivery vectors and mediators of biological signals across tissues. Here, by leveraging these functionalities, we show that EVs decorated with an antibody-binding moiety can be used as a modular delivery system for targeted cancer therapy.
PIEZO1 mechanically regulates the antitumour cytotoxicity of T lymphocytes
We identified PIEZO1 as a mechanical sensor to regulate the mechanical signaling that is critical for the cytotoxic T cells (CTLs) against tumor cells, creating potential venues to enhance the efficacy of targeted T cell immune therapies.
The Grinch got big for us with no physical consequences. But how do we prevent aneurysms from rupturing in real life?
They say that the Grinch’s heart grew three sizes in one day. In the land of fantasy, this makes him a happier person and a friendlier neighbor to the Whos. In real life, rapid cardiovascular expansion is a silent but deadly disease.
