Association between KCNJ11 rs5219 polymorphisms and gestational diabetes mellitus: A meta-analysis
Published in General & Internal Medicine
Essentially, our study strongly suggests that a specific gene variation, known as KCNJ11 rs5219, is significantly linked to a higher risk of GDM, especially when considering a particular genetic model. This gene seems to play a notable role in influencing who might be more prone to developing GDM during pregnancy. However, it is important to note that the relationship between this gene and GDM is not straightforward, and it varies depending on different factors, such as the genetic models used in studies and the populations being investigated. This complexity emphasizes the intricate nature of genetic influences on GDM. Our study's findings highlight the need for more research to dig deeper into the mechanisms behind this genetic association, considering differences among various populations. Understanding these genetic factors better could eventually lead to improved ways of identifying and treating individuals at risk of or affected by gestational diabetes.
