Prostate cancer remains one of the most prevalent malignancies among men globally, accounting for a significant proportion of cancer-related morbidity and mortality. With increasing life expectancy and improved diagnostic techniques, the incidence and detection rates of prostate cancer continue to rise, highlighting the critical need for advances in both diagnostic and therapeutic approaches. Recent breakthroughs in molecular biology, imaging technologies, and genetic profiling have significantly enhanced early detection and prognostic accuracy, allowing for more personalized patient care.

This Collection aims to present comprehensive insights into recent developments and cutting-edge research in prostate cancer diagnosis and treatment. Key topics include novel biomarkers for early detection, advances in imaging modalities such as multiparametric MRI and PET-PSMA, genomic and epigenetic factors influencing disease progression, and emerging therapeutic strategies including robotic-assisted surgery, radiotherapy advancements, immunotherapy, and precision medicine approaches. Additionally, the collection will explore mechanisms of resistance to therapy, the role of tumor microenvironment in disease evolution, and strategies to overcome treatment barriers. We invite contributions focusing on translational and clinical research, innovative diagnostic methods, therapeutic innovations, and studies that bridge fundamental discoveries with clinical application to improve patient outcomes in prostate cancer.

Keywords: prostate cancer, biomarkers, imaging, genomics, precision medicine, robotic surgery, radiotherapy, immunotherapy, tumor microenvironment

Lung cancer remains one of the leading causes of cancer-related mortality worldwide, although recent years have seen remarkable progress in its clinical management. This Collection aims to deepen the evolving landscape of lung cancer through a comprehensive lens, including early diagnosis, molecular profiling (through liquid and tissue), therapeutic innovation, and simultaneous care strategies. The Collection will gather original research, reviews, short reports or letters and case studies focused on:

advances in early detection and biomarker discovery and development;

the evolution of precision oncology and molecular profiling;

updates on systemic therapies, including immunotherapy and targeted agents;

novel treatment combination strategies,

the increasing integration of simultaneous care into multidisciplinary models for improving patient outcomes.

Keywords: lung cancer; precision oncology; immunotherapy; molecular diagnostics; simultaneous care