Highlights of the BMC Series - December 2025

Could one tooth unravel secrets of a mosasaur? Do whales’ deep breath hide secrets in it? How can teamwork ease surgery for young diabetics? Why do unemployed people miss access to care? How have viral pathogens emerged and evolved over time?
Highlights of the BMC Series - December 2025
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BMC Zoology - “King of the Riverside”, a multi-proxy approach offers a new perspective on mosasaurs before their extinction 

Mosasaurs are usually thought of as apex marine predators that lived during the Cretaceous period. However, in 2022, a mosasaurine tooth crown was found in the Hell Creek Formation, Morton County, North Dakota, a fossil locality lacking marine taxa but dominated by terrestrial and freshwater species. This discovery of a mosasaurine tooth crown raised questions whether mosasaurs really roamed freshwater rivers? or it had been carried from the ocean after death? 

From During et al. Fig. 2

To unravel these uncertainties, researchers have employed a multi-proxy approach and investigated the tooth’s chemical makeup through several isotope analyses (including carbon, oxygen, and strontium) and examining the tooth’s morphology and comparing it with known mosasaur species. The ‘chemical signature’ of mosasaurine tooth showed that the tooth was formed while the mosasaur lived in a freshwater environment and not in the marine.  

These findings suggest that mosasaurus adapted to freshwater environments and, due to this, mosasaurs survived and thrived in various ecological niches during the Late Cretaceous. This study challenges assumptions of mosasaurs as strict marine animals, showing us a much clear picture of how flexible and adaptable they were. 

BMC Veterinary Research Deep breath out: molecular survey of selected pathogens in blow and skin biopsies from North Atlantic cetaceans 

Several pathogens, such as morbillivirus, herpesvirus, Brucella spp., and avian influenza virus (AIV) are associated with whale health and population dynamics, affecting whales globally, including in the Northeast (NE) Atlantic. Therefore, pathogen surveillance becomes crucial in free-swimming whales, but pathogen surveillance in free-living whales are limited.

© VW Pics/Contributor via Getty Images

To understand what is happening with living humpback, sperm, and fin whales of the NE Atlantic, scientists used drones to collect ‘blow’ samples (whales exhale) and small skin samples. Further, scientists screened these samples through polymerase chain reaction (PCR), and they found that cetacean morbillivirus was present in the blows of two asymptomatic groups of humpback whales, one sperm whale in poor health and in the kidney of a stranded pilot whale. They also detected herpesviruses in several humpback whale groups and in one skin biopsy whereas AIV or Brucella bacteria were not detected in any samples.

These findings suggest that the use of drones for ‘blow sampling’ is an effective, minimally invasive sampling technique that can be used for pathogen surveillance in free-ranging cetaceans. Moreover, continued pathogen exposure monitoring is important for understanding disease dynamics, assessing health implications, and helping guide future conservation strategies. 

BMC Endocrine Disorders - Australasian periprocedural guideline for children and adolescents with diabetes mellitus 

Preparing children and adolescents with type 2 diabetes (T2D) for surgery is a challenging task for family and health care professionals (HCP), as during periprocedural period, young diabetics are at risk of low or high blood sugar. Additionally, due to the variety of insulin regimens, glucose monitoring methods, introduction of new medications, and varying levels of practitioner experience, managing T2D has become more complex. Therefore, it is essential to have clear guidelines to support healthcare staff of all backgrounds and ensure tailored treatment for each young patient.  

© supersizer via Getty Images

Through this study, researchers have developed a guideline using a co-design approach, involving doctors, nurses, diabetes specialists, anaesthetists, and families with lived experience. This guideline ensures an early checklist for everyone involved, keeping the guideline patient centric, defining procedure classifications (minor, major, elective, or emergency) and recommending blood glucose levels between 5-10 mmol/L throughout the perioperative period. It also guides the use of glucose monitors, insulin pumps, fasting, blood sugar management, and insulin regimens.

This study provides guidance through which healthcare providers can deliver safe, comprehensive, and patient-centered care throughout the periprocedural period. Also, the study underscores the need for a validated, nationally standardized protocol.  

BMC Health Services Research - Unmet need for healthcare services among unemployed people – findings from a national survey in Finland 

Have you ever thought how complicated healthcare access can be for people who are unemployed or lost their jobs? Researchers have analyzed the Healthy Finland Survey (2022–2023) to decode the use of healthcare services among unemployed people compared to people who are working. They also investigated how different health-related factors affect healthcare access among these individuals.   

©Maskot via Getty Images

After analyzing sociodemographic and health-related factors, researchers found that unemployed people were much more likely to have poorer overall health, including long‑term illnesses, psychological distress, limited functional ability, and reduced work capacity. Despite these complications, 23% unemployed individuals reported no need for a doctor, whereas 41% reported unmet needs. This failure to recognize the need for healthcare or access to healthcare is due to the high out-of-pocket payments, poor financial situation, and absence of employer‑supported healthcare. 

Further, this study reveals that unmet healthcare needs are particularly associated with poor work ability and long-term illness. The study highlights the need for a more proactive approach and low-threshold services to reach unemployed people early, prevent diagnostic delays, and ensure equitable healthcare access.  

BMC Infectious Diseases - A century of emergence: trends and patterns in human viral pathogens, 1900–2024, a systematic review 

Infectious diseases are one of the most consistent threats to global health. Over the past century, the world has seen emergence and re-emergence of many infectious diseases such as HIV/AIDS, SARS, Zika virus, COVID-19, and Mpox exposing gaps in surveillance infrastructure. Therefore, it is critical to understand the trends and patterns in human viral pathogens.

© d3sign via Getty Images

In this study, researchers have retrospectively analyzed the emergence and re-emergence of human pathogens from the 20th century to present and identified 212 viral pathogens that first appeared in humans between 1900 and 2024. They found that emergence peaked twice, once between 1950-1979 and another after 2000, reflecting advancements in molecular diagnostics, laboratory infrastructure, and global surveillance networks rather than sudden biological changes. Further, they found that RNA viruses dominated the emergence due to their high mutation rate and ability to cross species barriers. More than half of the viruses originated from animals or insects. Respiratory and febrile diseases were most prevalent, and United States, China, and Australia were common detection sites; however, this is likely due to differences in surveillance and research capacity rather than true epidemiological “hotspots”.  

Overall, the study highlights how technological, ecological, and socio-demographic factors shape viral emergence.

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Zoology
Life Sciences > Biological Sciences > Zoology
Veterinary Science
Life Sciences > Biological Sciences > Veterinary Science
Endocrine System and Metabolic Diseases
Life Sciences > Health Sciences > Clinical Medicine > Endocrinology > Endocrine System and Metabolic Diseases
Health Care Management
Humanities and Social Sciences > Business and Management > Industries > Health Care Management
Infectious Diseases
Life Sciences > Biological Sciences > Microbiology > Medical Microbiology > Infectious Diseases
Infectious-Disease Epidemiology
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