Behind the Paper

Modeling the Invasive Progression of Human Cancer

Surgical generation of orthotopic xenograft models that recapitulate the invasive progression of human bladder cancer.

Published in Protocols & Methods

Go to the profile of Guadalupe Lorenzatti Hiles
Guadalupe Lorenzatti Hiles
Senior Research Fellow, University of Michigan
Modeling the Invasive Progression of Human Cancer
Like

Share this post

Choose a social network to share with, or copy the URL to share elsewhere

Share with...

...or copy the link

This is a representation of how your post may appear on social media. The actual post will vary between social networks

Explore the Research

Nature
Nature Nature

A surgical orthotopic approach for studying the invasive progression of human bladder cancer - Nature Protocols

A small laparotomy is carried out, and human cancer cells are implanted into the mouse bladder lumen. This reproduces the pathobiological events of human bladder cancer invasion in mice.





References: 

1          Lorenzatti Hiles, G., Cates, A.L., El-Sawy, L. et al. A surgical orthotopic approach for studying the invasive progression of human bladder cancer. Nat Protoc 14, 738–755 (2019).

Go to the profile of Guadalupe Lorenzatti Hiles
Guadalupe Lorenzatti Hiles
Senior Research Fellow, University of Michigan

Follow the Topic

Biological Techniques
Life Sciences > Biological Sciences > Biological Techniques

Recommended Content

Cookie Settings

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website. You can decide for yourself which categories you want to deny or allow. Please note that based on your settings not all functionalities of the site are available.

Further information can be found in our privacy policy.

Cookie Control

Customise your preferences for any tracking technology

The following allows you to customize your consent preferences for any tracking technology used to help us achieve the features and activities described below. To learn more about how these trackers help us and how they work, refer to the cookie policy. You may review and change your preferences at any time.

Cookie policy Privacy policy
Always active, cannot be turned off
More information

These trackers are used for activities that are strictly necessary to operate or deliver the service you requested from us and, therefore, do not require you to consent.

More information

These trackers help us to deliver personalized marketing content and to operate, serve and track ads.

More information

These trackers help us to deliver personalized marketing content to you based on your behaviour and to operate, serve and track social advertising.

More information

These trackers help us to measure traffic and analyze your behaviour with the goal of improving our service.

More information

These trackers help us to provide a personalized user experience by improving the quality of your preference management options, and by enabling the interaction with external networks and platforms.