New Collection Launch: Eye–Brain Axis in Neurodegenerative Disease - Mechanisms and Diagnostics
Published in Neuroscience and General & Internal Medicine
We are pleased to announce a new collection in Neuroretina: Eye–Brain Axis in Neurodegenerative Disease - Mechanisms and Diagnostics.
The eye–brain axis has emerged as a compelling framework for understanding neurodegeneration. As accessible extensions of the central nervous system, the retina and optic nerve provide a unique window into brain pathology, where structural and functional changes may precede or reflect disease progression.
This collection brings together work that advances both mechanistic insight and diagnostic innovation across this interface.
Scope
We welcome high-quality submissions spanning experimental, clinical, and translational research, including:
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Mechanistic insight
- Neuroinflammatory signalling across retina and brain
- Microglial and astrocyte activation
- Neurovascular coupling and ocular perfusion
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Disease focus: retinal and optic nerve changes in disorders such as
- Multiple sclerosis (MS)
- Amyotrophic lateral sclerosis (ALS)
- Huntington’s disease
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Diagnostics and biomarkers
- Imaging-based markers (e.g. OCT, OCT-A)
- Functional testing (e.g. visual evoked potentials)
- Emerging digital biomarkers
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Models and translation
- Preclinical and transgenic models
- Imaging-guided tracking of visual pathway degeneration
The collection particularly encourages work integrating molecular, imaging, and clinical data, with clear translational relevance.
Why submit?
- Strong journal fit: dedicated to neuroretina research linking ophthalmology and neurology
- Open access visibility: global reach and accessibility
- Translational emphasis: focus on clinically meaningful advances
Submit your work
Submission deadline: 12 March 2027
We invite original research, reviews, and clinical studies that explore the diagnostic and mechanistic potential of the eye–brain axis. Submit your manuscript today and help shape the future of neurodegenerative disease diagnostics!
👉 Click here to explore more about the collection & submission guidelines!
I look after a portfolio of Ophthalmology journals within Biomedicine journals at Springer Nature.
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Neuroretina
This is a brand new open access journal, with a focus on using retinal imaging techniques alongside molecular and genetic markers to improve the understanding, diagnosis, and management of neurodegenerative diseases.
Related Collections
With Collections, you can get published faster and increase your visibility.
Oculomics in Neurodegenerative Disease: From Biomarkers to Early Diagnosis
Research focusing on the development of machine learning models, longitudinal imaging studies, comparative biomarker studies, and cross-disciplinary applications is especially encouraged. Submissions may also discuss the integration of oculomics in clinical workflows and the challenges in translating findings from research to bedside.
Topics of Interest include (but are not limited to):
· Retinal and optic nerve biomarkers in Alzheimer’s and Parkinson’s disease
· OCT-based structural changes in neurodegeneration
· Retinal vasculature and microvascular anomalies in dementia risk
· AI and deep learning in ocular image analysis for neurodegenerative disease detection
· Correlation of ocular biomarkers with neuroimaging (MRI, PET) findings, and blood-based biomarkers
· Oculomic approaches in multiple sclerosis and demyelinating disorders
· Role of the retina in disease progression tracking and outcome prediction
· Multimodal oculomics combining imaging, genomics, and clinical data
· Challenges in standardizing ocular biomarkers for clinical application
· Population-based screening strategies using oculomics
· Animal models and experimental research linking retinal changes to brain pathology
Publishing Model: Open Access
Deadline: Oct 01, 2026
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