Despite growing evidence suggesting a viral component in endodontic infections, no comprehensive synthesis currently exists. This systematic review and meta-analysis aim to fill that gap, providing reliable data to support future diagnostic and therapeutic strategies.This protocol was developed following the PRISMA-P guidelines and registered in PROSPERO to ensure methodological transparency. It defines clear inclusion and exclusion criteria, outlines a comprehensive search strategy across multiple databases, and specifies the use of the ROBINS-I tool for risk of bias assessment in non-randomized studies. Data synthesis will include both qualitative analysis and meta-analysis, when appropriate, using random-effects models to account for study heterogeneity.
Why is important to make a good protocol for conducting reviews?
A protocol is essential to ensure a transparent, reproducible, and methodologically rigorous approach to reviewing the prevalence of viral infections in acute apical abscesses.
Published in Biomedical Research, General & Internal Medicine, and Public Health
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Dental Diseases
Life Sciences > Health Sciences > Clinical Medicine > Diseases > Dental Diseases
Oral Microbiology
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BDJ Open
This is an international, peer-reviewed, open-access, online-only journal publishing dental and oral health research from all disciplines. The journal is owned by the British Dental Association (BDA) and is the sister journal of the British Dental Journal.