Go to the profile of Ashraf Zarkan

Ashraf Zarkan

Research Fellow, University of Cambridge
  • United Kingdom

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Inhibiting indole signalling offers a potential strategy for combatting antibiotic persisters
Scientific Reports
Behind the Paper

Inhibiting indole signalling offers a potential strategy for combatting antibiotic persisters

A lesser-known aspect of antibiotic resistance is the ability of bacterial persister cells to survive antibiotic treatment through dormancy. We find that indole signalling increases E. coli quinolone persisters, suggesting that indole inhibition may provide a method to enhance quinolone antibiotics

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