Proteomic analysis of the combined effects of cannabigerol and 3-O-ethyl ascorbic acid on kinase-dependent signalling in UVB-irradiated human keratinocytes
Phytocannabinoid CBG together with EAA, a stable, lipophilic derivative of the vitamin C, recovered human skin cells irradiated by UV light. Their effects on kinases were manifested even after 24 hours.
Effects of CBG and EAA were linked to reduced modification of keratinocyte proteins by 4-HNE.