Portimine A toxin causes skin inflammation through ZAKα-dependent NLRP1 inflammasome activation
In 2020 and 2021, a mysterious skin disease affected more than a thousand Senegalese fishermen, raising concern and international attention. The origin of this disease: a toxin produced by the marine microalga Vulcanodinium rugosum triggers a severe inflammation of the skin cells.
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great study - check this out