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Recent Comments
Fascinating story! Appreciate the great efforts from you "cool" guys who guided the direction of itaconate research, one of if not THE most significant discoveries in immunometabolism area in the past decade.
one of the remaining questions is, how to cope with the appearing paradox that itaconate can enhance the action of oxidative species, yet inhibit NLRP3 activity on BMDMs, given the main stream belief that mtROS is a trigger of NLRP3 activity.
Perplexing yet fascinating, beauty of science!