Accelerated discovery of antiviral antibodies
An antibody-discovery pipeline integrating single-cell mRNA-sequence analysis, bioinformatics, synthetic biology and high-throughput functional analyses enables the rapid discovery of potent human monoclonal antibodies against viral pathogens.
Published in Bioengineering & Biotechnology
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Chief Editor, Nature Biomedical Engineering, Nature Research
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Nature Biomedical Engineering
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The cover illustrates antiviral human monoclonal antibodies, in this case against the Zika virus, discovered via a pipeline integrating single-cell mRNA-sequence analysis, bioinformatics, synthetic biology and high-throughput functional analyses.
See Gilchuk et al.
Image: Molecular structures from David S. Goodsell and the RCSB PDB. Cover design: Alex Wing.