Accelerated discovery of antiviral antibodies
An antibody-discovery pipeline integrating single-cell mRNA-sequence analysis, bioinformatics, synthetic biology and high-throughput functional analyses enables the rapid discovery of potent human monoclonal antibodies against viral pathogens.
Published in Bioengineering & Biotechnology
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Chief Editor, Nature Biomedical Engineering, Nature Research
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Nature Biomedical Engineering
This journal aspires to become the most prominent publishing venue in biomedical engineering by bringing together the most important advances in the discipline, enhancing their visibility, and providing overviews of the state of the art in each field.
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The cover illustrates antiviral human monoclonal antibodies, in this case against the Zika virus, discovered via a pipeline integrating single-cell mRNA-sequence analysis, bioinformatics, synthetic biology and high-throughput functional analyses.
See Gilchuk et al.
Image: Molecular structures from David S. Goodsell and the RCSB PDB. Cover design: Alex Wing.