Amplification-free nucleic-acid testing
An electrical biosensor combining CRISPR/Cas9 and a graphene field-effect transistor detects target genes in purified genomic samples at high sensitivity, within 15 minutes, and without the need for amplification.
Published in Bioengineering & Biotechnology
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Chief Editor, Nature Biomedical Engineering, Nature Research
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Life Sciences > Biological Sciences > Biotechnology
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Nature Biomedical Engineering
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The cover illustrates an electrical biosensor for nucleic acids that relies on the binding of target sequences to Cas9 immobilized on a graphene field-effect transistor.
See Hajian et al.
Image: Ella Maru Studio.