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Peritumoural immunomodulatory scaffolds

A peritumourally implanted macroporous scaffold releasing small molecules and antibodies to suppress regulatory T cells and to attract and stimulate effector T cells enhanced endogenous antitumoural responses in mice bearing aggressive tumours.
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Pep Pàmies
Chief Editor, Nature Biomedical Engineering, Nature Research
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Systemic enhancement of antitumour immunity by peritumourally implanted immunomodulatory macroporous scaffolds - Nature Biomedical Engineering

A peritumourally implanted macroporous scaffold releasing small molecules and antibodies to suppress regulatory T cells and to attract and stimulate effector T cells enhanced endogenous antitumoural responses in mice bearing aggressive tumours.

The cover illustrates that a scaffold releasing specific small molecules and antibodies can suppress regulatory T cells and attract and stimulate effector T cells when implanted peritumourally in mice.

See Majedi et al.

Image: Ella Marushchenko and Ekaterina Zvorykina, Ella Maru Studio, Inc. Cover design: Allen Beattie.
Go to the profile of Pep Pàmies
Pep Pàmies
Chief Editor, Nature Biomedical Engineering, Nature Research

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