Phenotyping intratumoural heterogeneity
A method that identifies patterns of tumour heterogeneity in intact biopsy samples using 3D light-sheet microscopy stratifies patients by tumour stage.
Published in Bioengineering & Biotechnology
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Nature Biomedical Engineering
This journal aspires to become the most prominent publishing venue in biomedical engineering by bringing together the most important advances in the discipline, enhancing their visibility, and providing overviews of the state of the art in each field.
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The cover illustrates patterns of vascular heterogeneity in cleared solid tumours identified through light-sheet microscopy.
https://dx.doi.org/10.1038/s41551-017-0139-0
Image from Nobuyuki Tanaka and Per Uhlén.