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Prolonged immune activation via polymer–STING condensates

A polyvalent STING agonist prolongs the activation of innate-immunity pathways through the formation of STING condensates, and leads to synergistic therapeutic outcomes in vivo when combined with the STING ligand cGAMP.
Go to the profile of Pep Pàmies
Pep Pàmies
Chief Editor, Nature Biomedical Engineering, Nature Research
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Prolonged activation of innate immune pathways by a polyvalent STING agonist - Nature Biomedical Engineering

A polyvalent STING agonist prolongs the activation of innate-immunity pathways through the formation of STING condensates, and leads to synergistic therapeutic outcomes in vivo when combined with the STING ligand cGAMP.

Image: Xianzhi Chen, Shenyang Zhiyan Science and Technology Co. Ltd. Cover design: Allen Beattie.

Go to the profile of Pep Pàmies
Pep Pàmies
Chief Editor, Nature Biomedical Engineering, Nature Research

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Life Sciences > Biological Sciences > Biotechnology

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