Ultrasound-enabled targeting of specific brain circuits
The combination of focused ultrasound and virally encoded receptors engineered to be activated by a designer drug enables, on intravenous administration of the drug, the non-invasive activation or inhibition of brain regions in mice, with cell-type and spatiotemporal specificity.
Published in Bioengineering & Biotechnology
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Chief Editor, Nature Biomedical Engineering, Nature Research
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Biotechnology
Life Sciences > Biological Sciences > Biotechnology
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Nature Biomedical Engineering
This journal aspires to become the most prominent publishing venue in biomedical engineering by bringing together the most important advances in the discipline, enhancing their visibility, and providing overviews of the state of the art in each field.
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The cover illustrates the non-invasive modulation of brain circuits, with cell-type and spatiotemporal specificity, via focused ultrasound and virally encoded receptors engineered to be activated by a designer drug.
See Szablowski et al., https://doi.org/10.1038/s41551-018-0258-2
Image: Maayan Harel and Jerzy Szablowski. Cover design: Alex Wing.