What is this collection about?

Macrophages are a key component of the tumour microenvironment and influence tumour progression, immune-cell infiltration, and responses to immunotherapy. This cross-journal Collection from Nature Immunology, Nature Communications, Communications Biology, Communications Medicine and Scientific Reports seeks research that advances understanding of tumour-associated macrophages, including the mechanisms governing their plasticity and heterogeneity, their interactions with stromal and immune cells, the role of ontogeny in shaping their behaviour, and their impact on therapeutic approaches.

Why is this collection important?

Macrophages are increasingly recognised as central regulators of anti-tumour immunity and therapeutic response. Understanding how these cells acquire pro- or anti-tumour functions, adapt to diverse tumour environments, and influence treatment outcomes could inform the next generation of cancer therapies. By bringing together research across immunology, cancer biology and translational medicine, this Collection aims to highlight emerging discoveries and foster progress in a rapidly evolving field.

Why submit to a collection?

Collections like this one help attract and promote high-quality science. They are led by internal In-House Editors and supported by a dedicated team of Commissioning Editors and Managing Editors at Springer Nature. Collection manuscripts typically see higher citations, downloads, and Altmetric scores, and provide a one-stop-shop on a cutting-edge topic of interest.

Who is involved?

Nature Communications is edited by in-house professional editors.

Nature Immunology is edited by in-house professional editors.

Communications Biology is edited by both in-house professional editors and Editorial Board Members.

Communications Medicine is edited by both in-house professional editors and Editorial Board Members.

Scientific Reports is managed by in-house professional editors and edited by Editorial Board Members.

Our editors work closely together to ensure the quality of our published papers and consistency in author experience.

How can I submit my paper?

Visit the Collection page to find out more about this collection and submit your article.