Delivering Light on Topical Collection “Discover Advances in the Design and Synthesis of Nano- Optics and Applications”
Published in Bioengineering & Biotechnology, Chemistry, and Earth & Environment
It was tuned mono-coloured Silicon Nanophotonics incorporating Fluorescein (Fl) confined within silica nanoparticles (SiO2-Fl NPs). Silicon within modified organosilanes permitted to tune delivery of photons. Therefore, varied emission intensities were calibrated varying the as Laser dye incorporation. It was observed the particular characteristic of dimeric formation that showed higher emissions than single ones ( https://link.springer.com/collections/iffbffbjdg).
This fact opened to the discussion about electronics and topological photonics such as based on nanoantenna and resonant phenomena. The dimeric forms were spontaneously formed by non-covalent interactions between modified inter-nano-surfaces with silanol groups and Fl Laser dyes with different chemical groups, electronic domains of interactions and Van der Walls forces. It was applied these Nano-emitters for Anabaena sp. from Patagonia lakes. The Nano-Biostructures maintained longitudinal shapes with pass of time as natural ones exist in absence of nanolabellers.
The natural bio-optics with two natural Photosystems nominated as I and II (PS I and II) permitted to couple the light delivered from SiO2-Fl NPs as nanolabellers. In this manner, it was generated higher emissions towards longer emissions wavelengths stimulating within shorter excitation intervals of wavelengths. So, it was showed and discussed how the non-classical light delivery summed to light scattering phenomena from other modes of resonances afforded to different emission modes of energy. The non-classical light produced in the bioimaging event was explained by confined laser dyes within the nanoscale producing photon delivery to targeted acceptor bio-optics. The nano-assembly produced shapes with different scattering and intrinsic electronic properties that generated new bioluminescence energy emission modes towards the NIR non-observed before. In this manner, from single nano emitters to dimeric forms and further nano-bio-assembling, it was generated different optical pathways. This fact afforded to the discussion as well on how this simple nanotechnology could permit speciation of unicellular organism. In this regard, it was showed insights in this field and compared with previous results recorded by us with Microcystis aeruginosa sp.
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The discovery of new therapeutic agents has increasingly relied on the integration of medicinal chemistry synthesis with computational approaches to accelerate the identification, optimization, and development of biologically active molecules. Recent advances in computational chemistry have significantly improved the efficiency of lead identification and optimization while reducing the cost and time associated with conventional drug discovery.
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The Collection welcomes original research articles, comprehensive reviews, mini-reviews, and perspective articles covering experimental and computational studies that address current challenges in medicinal chemistry and translational drug discovery.
Expected Impact
The proposed collection will serve as a comprehensive resource for emerging methodologies and recent advances in computationally guided medicinal chemistry. It is expected to attract high-quality submissions from international researchers and foster collaborations across academia, industry, and pharmaceutical research organizations. By combining experimental medicinal chemistry with computational approaches, the collection will contribute significantly to accelerating the development of safer and more effective therapeutic agents.
Specific Key Topics:
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