This Topical Collection in Archives of Women’s Mental Health spotlights the diagnosis and treatment of mental health problems across the menopausal transition, with an emphasis on hormonal approaches. 

We welcome studies that clarify when, how, and for whom menopausal hormone therapy (MHT) improves depressive, anxiety, cognitive, and sleep symptoms; compare MHT with antidepressants and psychotherapies; and evaluate combination or augmentation strategies.

Priority areas include route and dosing (e.g., transdermal vs. oral), timing across peri- to postmenopause, safety and contraindications, shared decision-making, and patient-reported outcomes. We also encourage submissions on special populations (e.g., premature ovarian insufficiency, surgical menopause, severe mental illness, cardiometabolic comorbidities, breast cancer survivorship), mechanistic work linking hormonal dynamics to neurobiology, and implementation research across psychiatry, primary care, and gynecology.

We invite original research, reviews, systematic reviews, or short communications that advance equitable, evidence-based care for midlife mental health.