Implementation research serves as a cornerstone in the advancement of evidence-based healthcare. By bridging the gap between scientific evidence and practical implementation, it plays a critical role in translating research findings into effective policies and programs. The real-world application of healthcare interventions often reveals challenges that were not anticipated during the research phase. Thus, understanding the intricacies of program implementation within the broader context of health systems is essential for ensuring the sustainability and scalability of healthcare innovations.

Implementation science goes beyond merely identifying gaps between research and practice; it offers a systematic approach to uncovering unknown barriers and addressing them with feasible, context-specific solutions. This approach not only enhances the effectiveness of healthcare interventions but also contributes to the overall strengthening of health systems. The field holds the potential to inform policy-making, optimize resource allocation, and improve service delivery, particularly in settings where health systems are under-resourced or face unique challenges.

This collection aims to explore the role of implementation research in strengthening health systems, with a particular focus on its ability to bridge the gap between evidence and practice. It seeks to provide a comprehensive overview of how implementation science can be leveraged to address both known and unknown challenges in healthcare delivery. Contributions are invited from scholars who are conducting empirical research, theoretical analyses, or opinion pieces that examine the impact of implementation science on health systems. Topics of interest include, but are not limited to, case studies of successful implementation strategies, evaluations of policy impact, identification of systemic gaps, and the development of innovative solutions tailored to local contexts.

Keywords:Health systems, Implementation research, evidence, health service delivery, health service, health policy

This collection is dedicated to advancing our understanding of chronic disease management through the lens of health systems innovation. We invite original research articles and rigorous reviews (systematic, narrative, or scoping) that examine how integrated care models and advanced health service frameworks can transform the management of long-term conditions. Our aim is to highlight research that connects clinical practice with the operational, organizational, and financial structures of health systems.

Submissions should focus on studies that explore and evaluate innovative approaches to care delivery within health systems, highlighting topics such as:

• Integrated Care Models: Investigations into coordinated care strategies that align medical and nursing practices with broader service delivery systems, ensuring seamless transitions between primary, secondary, and community care.

• Organizational Innovations: Evaluations of new management models and care strategies that optimize resource allocation, enhance patient safety, and streamline service delivery within complex health systems.

• Nurse-led and Multidisciplinary Care: Analyses of care strategies led by nursing professionals and multidisciplinary teams, emphasizing their roles in facilitating patient-centered care within structured health service environments.

• Health Economics and Service Sustainability: Economic evaluations and cost-effectiveness analyses of chronic care interventions that inform policy and practice changes within health systems.

• Digital Health and Care Coordination: Studies on the implementation and impact of digital technologies and telemedicine in improving chronic care management, with a focus on enhancing system-wide efficiency and patient outcomes.

• Health System Reforms: Research on policy-driven and organizational reforms aimed at integrating chronic disease management into the broader health services framework, ensuring that care models are both sustainable and scalable.

This collection of articles aims to explore and promote the synergy between clinical excellence and health system innovation, with the goal of highlighting how robust service delivery models can not only optimize clinical outcomes but also enhance patient satisfaction and improve overall quality of life. We are seeking studies that deeply address the operational, financial, and organizational aspects of chronic care within health systems, emphasizing the critical role of a well-structured healthcare system in supporting the treatment and management of chronic diseases.

In particular, we welcome manuscripts that explore innovative approaches to the design and implementation of healthcare services, with a focus on integrated care models, financial sustainability, and organizational efficiency. Our intention is to create a collection that not only contributes to high-quality academic research but also influences healthcare policies globally, providing practical and applicable solutions to address the challenges of international healthcare systems.

Keywords: Chronic disease care, Community Care, nursing care, patient engagement, health economic evaluation