The human gut microbiome plays a critical role in maintaining health and modulating disease processes. Its composition evolves across the lifespan under the influence of diet, lifestyle, aging, and environmental exposures. Disruption of gut microbial balance—known as dysbiosis—has been implicated in the pathogenesis of various chronic conditions, including autoimmune, metabolic, neurological, and inflammatory diseases.

This Collection welcomes submissions that explore the mechanistic, clinical, and translational aspects of gut microbiota in human health, with particular interest in:

The gut–brain, gut–heart, gut–cancer, and gut–joint axes

Gut dysbiosis and its immunological and metabolic consequences

Microbial metabolites and host-microbiome interactions

Microbiome-based diagnostics, therapeutic interventions, and biomarkers

We invite contributions including but not limited to:

Original research articles based on clinical, in vivo or in vitro studies

Reviews summarizing recent advances or proposing new frameworks

Perspective or opinion pieces that highlight emerging concepts or challenges

This Collection aims to enhance our understanding of the gut microbiome's contribution to health and disease and to inspire microbiome-based strategies for improving human well-being.

Keywords: Gut microbiome; Gut-organ-axis; chronic diseases; 16S rRNA; metagenomics

Cardiovascular diseases remain a major global health challenge worldwide, continuing to be a leading cause of morbidity and mortality despite substantial advances in prevention and treatment. In recent years, progress in cardiovascular diagnostics, interventional techniques, and arrhythmia management has significantly improved patient care; however, important challenges persist, including timely diagnosis, individualized risk stratification, optimization of interventional strategies, and long-term outcome improvement. These unmet needs highlight the necessity for continued innovation and multidisciplinary research efforts in cardiovascular medicine.

This Collection aims to highlight recent advances in cardiovascular diagnostics, interventional therapies, and arrhythmia management, with a focus on clinically relevant and translational research. We welcome submissions addressing interventional cardiology procedures, catheter ablation techniques, three-dimensional electroanatomical mapping, mechanisms of cardiac arrhythmias, cardiovascular imaging, acute coronary syndromes, and hypertension. Contributions that enhance understanding of disease mechanisms, improve procedural outcomes, or inform clinical decision-making are particularly encouraged.

By bringing together high-quality experimental, clinical, and translational studies, this Collection seeks to advance scientific knowledge, support the development of improved therapeutic strategies, and foster global collaboration in the field of cardiovascular medicine.

Keywords:

Cardiology; Arrhythmia; Ablation; 3D mapping; Interventional cardiology; Hypertension; Acute coronary syndrome; Cardiovascular imaging; COVID-19