Unlocking mushroom treasures: the untold story for reconstructing the biosynthetic network of type II ganoderic acids in engineered yeast
Type II ganoderic acids (TIIGAs) have excellent medicinal value and can also be serve as valuable nutraceutical ingredients, yet their natural production remains limited. We have deciphered the biosynthetic network of TIIGAs and established a platform for their efficient production in yeast.