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Synaptogenesis: A Key Process in Alzheimer's Disease (AD)
Understanding how synaptogenesis is affected in AD provides essential insights into disease progression and opens avenues for therapeutic intervention.
Exploring iPSC-Derived Cells in Alzheimer’s Research: From Mouse Models to Human Insights
The development of induced pluripotent stem cells (iPSCs) has revolutionized research into Alzheimer’s disease (AD), particularly in understanding amyloid-beta (Aβ) pathology and immune system interactions.
Age-Related Cellular Changes in the Hippocampus: Insights from Alzheimer’s Disease Models
Age-related changes in hippocampal cell populations include early synaptic loss in neurons, hyperactivation of microglia, reactive astrogliosis, and declining neurogenesis in the dentate gyrus.
The Critical Role of Cell Types in Alzheimer’s Disease
Alzheimer’s disease (AD) is widely known for its characteristic features, such as amyloid plaques and neurofibrillary tangles, but the role of different brain cell types in the progression of the disease is becoming increasingly important in research.
AI in Proteomics Data Analysis: Revolutionizing Protein Research
Artificial intelligence (AI) has emerged as a transformative tool, enhancing data processing, pattern recognition, and prediction in proteomics. This integration is accelerating discoveries and fostering deeper understanding in fields like drug development, biomarker discovery, and systems biology.
Differential Dynamics of Beta-Amyloid in Healthy vs. Alzheimer’s Affected Brains
Beta-amyloid plays a dual role in brain health and disease. In the normal brain, it supports critical processes, while in AD, its dysregulation contributes to neurodegeneration. A nuanced understanding of these mechanisms is essential for developing effective treatments .