CD2: A Plug-and-Play CAR-T Upgrade Strategy to Overcome Exhaustion and Enhance Anti-Tumor Potential
The link between CAR-T cells and cancer cells isn't very stable. Boosting CD2 levels – like giving it a stronger anchor – makes this connection much stronger. This improved connection (which scientists call an 'immunological synapse') helps the CAR-T cells work better from the ground up.