Structure-function and mechanistic analyses of a nickel-dependent sulfonamide synthase
A cupin superfamily enzyme SbzM catalyzes the formation of sulfonamide moiety in the biosynthesis of a sulfonamide natural antibiotic altemicidin. Here, we report the structure-function and mechanistic analyses of AmSbzM by in vitro characterization, crystallization, mutagenesis and calculations.
The Story Behind the Paper: In vitro antimalarial activity of phytochemicals from Bombax costatum via inhibition of β-hematin formation
My colleague Hassan and I have collaborated since our MSc (2016), united by a shared mission: fighting malaria. Growing up in Nigeria, we saw its devastating toll. With Africa bearing 70% of global cases, we knew this was where we belonged
Theoretical Considerations on Transition Metals Sulphides Precipitation in Alloyed Steels
Non-dimensional analysis and rules of thermochemical heat treatments permitted the formulation of a relative (statistically well correlated) ranking of sulphidising ability for transition metals and models to compute their amount in the metallic structure of Fe-C alloys
Behind the paper: Protic ionic liquids as binders for carbon paste electrode fabrication
A recurring challenge across all electrochemistry systems is achieving fast and efficient electron transfer at electrode surfaces. While attention is paid to the active electrode material, our work shows that a less obvious component—like a binder in a graphite electrode —can play a decisive role.