Nature Chemistry
A monthly journal dedicated to publishing high-quality papers that describe the most significant and cutting-edge research in all areas of chemistry, reflecting the traditional core subjects of analytical, inorganic, organic and physical chemistry.
The Kong group report a Ni-catalyzed enantioselective C(sp³)–H alkylation of saturated heterocycles using olefins, enabling efficient construction of chiral C(sp³)–C(sp³) bonds. Applications include late-stage drug diversification and concise syntheses of bioactive alkaloids.
A glycan that performs catalysis
We reported a synthetic glycan sequence capable of catalyzing a chemical reaction. The design features an aromatic recognition site along with a reactive functional group connected via a folded glycan turn, facilitating the recruitment and Pictet-Spengler functionalization of an aromatic moiety.
Isolation of a planar π-aromatic Bi5– ring in a cobalt-based inverse sandwich-type complex
Monocyclic aromatic molecules are well-known in organic chemistry and for coordination chemistry. In contrast, isoelectronic cycles comprising (semi)metal atoms only are much rarer. We present Bi5−, the so far elusive heaviest analogue of (C5H5)− which we trapped in an inverse-sandwich-type complex.
Behind the Paper: Catalyst self-assembly accelerates bimetallic light-driven water splitting
Light-driven hydrogen evolution from water holds promise for applications in synthetic fuels. Here, light-harvesting molecular catalysts noncovalently self-assemble into nanoscale aggregates for efficient photoelectrochemical hydrogen generation from water.
Squeezing Cells for High-Throughput Discovery of Phase Separating Proteins
On March 18, 2024, Our team from the College of Life Sciences & Technology, HUST published a research article titled "High-Throughput and Proteome-wide Discovery of Endogenous Biomolecular Condensates" in the Nature Chemistry.
Asymmetric alkene aminoarylations...with a Smiles:-)
We report here how chiral arylsulfinylamides can be used as "all-in-one" reagents for the visible light-mediated asymmetric aminoarylation of alkenes