Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Healthcare & Nursing
Procyanidin C1 is a natural agent with senolytic activity against ageing and age-related diseases
Advancements of studies with model organisms that cellular senescence drives ageing and age-related pathologies have elicited widespread efforts to identify compounds of a potential to selectively kill senescent cells, now termed as 'senolytics'.
GWAS for lung function with adjustment for exhaled nitric oxide levels as airway inflammation indicator
We performed a GWAS for lung function with adjustment for exhaled nitric oxide (FeNO) levels to account for type 2 airway inflammation. Our study identified the genetic locus most strongly associated with airway obstruction in the Japanese population and new genetic loci associated with FeNO.
When your body attacks itself – BTK inhibition shows promise for the treatment of chronic spontaneous urticaria (an autoimmune disease)
In a recent clinical trial, patients who had chronic spontaneous urticaria (CSU) for more than 6 months that would not respond to high doses of standard treatment (H1-antihistamines) – were enrolled to evaluate a “BTK blocker” drug, called, "fenebrutinib".