My new study offers insights into the dynamic interplay between cancer site, stage, and HRQoL trajectories during systemic and radiation therapy. Findings revealed that HRQoL scores differ for cancer survivors based on cancer sites and stages. For instance, the most diminished scores were consistently identified among patients confronted by advanced-stage (stage IV) cancer. Notably, our analysis further underscores the distinct HRQoL profiles associated with varying cancer sites, with throat, brain, lung, blood, and liver cancer survivors encountering markedly lower HRQoL compared to their counterparts diagnosed with breast, pancreatic, oral, or cervical cancer. By substantiating these associations, our study contributes to a more complete understanding of the intricate relationship between cancer characteristics and patients' quality of life outcomes.

Our findings advocate for an enhanced Bangladeshi cancer patient care model through timely interventions or programs, early detection or diagnosis, tailored treatments, and physical activity promotion to bolster HRQoL outcomes.