Go to the profile of Dan G. Duda

Dan G. Duda

Professor and Scientific Director, Transplant Oncology and Therapeutics, Houston Methodist Research Institute
  • United States of America
Nature Communications
Behind the Paper

STING Agonism and B Cells in Liver Cancer: How Immune Activation Can Drive Both Tumor Control and Metastasis—and Why Targeting Regulatory B Cells Can Unlock Durable Anti-Tumor Immunity

Immunotherapy can potently activate anti-cancer immunity, yet liver cancer often resists it. Our new research reveals one reason why: STING agonism or PD1/VEGFR2 blockade increases regulatory B cells that suppress T cells. Targeting these B cells can restore the immune balance and block metastasis.
Go to the profile of Dan G. Duda
Dan G. Duda
Jan 21, 2026

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