Go to the profile of Jie Zhang

Jie Zhang (He/Him)

Postdoctoral Researcher, Guangzhou Institutes of Biomedicine and Health
  • China

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Unveiling the Mysteries of the CTCF R567W Mutation in Neurodevelopmental Disorders
Nature Communications
Behind the Paper

Unveiling the Mysteries of the CTCF R567W Mutation in Neurodevelopmental Disorders

Our team uncovers the mechanism behind a clinically relevant mutation in the architecture protein CTCF and its inability to properly regulate 3D genome folding, resulting in neurodevelopmental disorders. This study provides valuable disease models for uncovering CTCF-associated pathogenesis.

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