AF1q is a universal marker of neuroblastoma that sustains N-Myc expression and drives tumorigenesis
AF1Q is an oncogene with roles in leukemia and solid tumor progression. Despite its expression in neural tissues, no role for AF1Q in tumors of neural origin has been reported. We found AF1Q is a universal marker of neuroblastoma that is essential for neuroblastoma cell survival and tumorigenicity.