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Streamlining DNA Mutation Detection: A Breakthrough with Phosphorothioated DNA-guided Endonuclease Excision

Detecting low-frequency DNA mutations remains a daunting task due to the background noise caused by wild-type (WT) DNA. In this article, we present a recent breakthrough that simplifies DNA mutation detection by eliminating WT DNA background using phosphorothioated DNA-guided endonuclease excision.

Meiping Zhao

Jul 27, 2023

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Enhancing Clinical Mutation Detection: A Game-Changing Molecular Approach

Meet sgDNase, a revolutionary molecular tool for detecting low-frequency mutations with single-nucleotide precision. It elevates variant allele frequencies, enabling diverse mutation detection methods. Cost-effective and transformative, sgDNase strongly advances precision cancer therapy.

Meiping Zhao

Sep 17, 2023

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Meiping Zhao (She/Her)

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Streamlining DNA Mutation Detection: A Breakthrough with Phosphorothioated DNA-guided Endonuclease Excision

Enhancing Clinical Mutation Detection: A Game-Changing Molecular Approach

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