Divalent and multivalent cations control liquid-like assembly of poly(ADP-ribosyl)ated PARP1 into multimolecular associates in vitro
We explain the role of poly(ADP-ribose) and biology relevant cations in the formation of condensates and points to the direct involvement of poly(ADP-ribosyl)ated PARP1 in the regulation of DNA repair via condensate formation.