Modular synthesis of chiral 1,n-diols via photo/nickel co-catalysis
The Kong group developed a photo-HAT/nickel synergistic strategy for directly converting bulk chemicals like ethylene glycol and 1,3-propanediol into optically pure 1,2- and 1,3-diols. This method avoids toxic metal catalysts and complex precursors, enabling sustainable asymmetric synthesis.