Go to the profile of Wang dianheng

Wang dianheng

Postdoctoral, Chinese Academy of Medical Sciences & Peking Union Medical College
  • China
Cellular & Molecular Immunology
Behind the Paper, Cancer in understudied populations Hub

Gasdermin E mediating lysosome-pore formation curbs pancreatic ductal adenocarcinoma via IFN-γ/IFN-β/TGF-β cocktail mRNA-LNP

Our study is the first to identify GSDME-mediated, lysosome-dependent cell death, revealing a novel lysosome-targeted killing mechanism co-regulated by three cytokines. Combined with the LNP system for PDAC targeting provide a new therapeutic direction. Published in Cellular & Molecular Immunology
Go to the profile of Wang dianheng
Wang dianheng
Jan 30, 2026

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