Communications Biology
An open access journal from Nature Portfolio publishing high-quality research, reviews and commentary in all areas of the biological sciences, representing significant advances and bringing new biological insight to a specialized area of research.
Phosphorelay systems found in fungi contain several hybrid histidine kinases that transfer phosphoryl groups to the same His-phosphotransferase. This many-to-one mechanism is promoted through a low affinity for interaction and a transient phosphorylation.
RECORD: A novel behavioral task battery to study complex decision-making in rodents
The complexity of behavioral decision making and the influence of various factors, such as stress and environment, make it difficult to draw parallels between rodent decision-making and other species without the development of novel task batteries. Described here as RECORD.
Mycofluidics of clocks in single filaments of Neurospora crassa
We show single filaments in the model system Neurospora crassa have a biological clock. We also develop model of the clock in single filaments that is supported by microfluidics data and provides an explanation for long distance (mm) synchronization of clocks in filaments.
Biomarkers for ideal protein: rabbit diet metabolomics varying key amino acids
This paper primarily aims to explore ideal protein biomarker signatures through both targeted and untargeted metabolomics analysis in a rabbit model.
Automated assessment of cardiac dynamics in aging and dilated cardiomyopathy Drosophila models using machine learning
Our platform uses deep learning to segment optical microscopy images of Drosophila hearts, facilitating the quantification of cardiac parameters for aging and dilated cardiomyopathy. Moreover, using a machine learning approach we able to predict cardiac aging with high accuracy.
A new automated, multiplex approach to studying shear stress mechanotransduction of circulating cells
As the mechanobiology of immune and cancer cells is gaining interest, we developed an easy to adopt, off-the-shelf system for subjecting many different samples to repeated cycles of fluid shear stress.
Mercury - the invisible contaminant that could be driving population declines among migratory shorebirds along the East Asian-Australasian Flyway
Over one-third of the sampled shorebirds along the East Asian-Australasian Flyway are facing Hg risk. Tringa genus in South China was at the highest risk. Feather Hg was best explained by feathers' moulting region, while habitat preference, diet, and forage stratum were less important.
Unveiling the Genetic Landscape of Fuchs Corneal Dystrophy Through a Multi-Ancestry GWAS
Explore pivotal findings from a genome-wide association study on Fuchs Corneal Dystrophy, highlighting the contributing roles of laminins, collagen, and endothelial cell regulation.