Nature Communications
An open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences.
Synthesis and versatile reactivity of scandium phosphinophosphinidene complexes
Due to the energy mismatching between the frontier orbitals of rare-earth metal and ligand atom, the rare-earth metal-phosphorus multiple bonds are very unstable. This Behind introduces our group’s struggling trip to the first rare-earth monometallic phosphinidene complex during the past 10 years.
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma
Ewing sarcoma is a pediatric cancer characterized by chimeric EWSR1-ETS fusion oncogenes (in 85% EWSR1-FLI1). In our recent study, we showed that EWSR1-FLI1 hijacks the developmental transcription factor SOX6, which contributes to tumor growth but also increases sensitivity toward oxidative stress.
Great or small, Legionella can secrete it all
By Amit Meir, ISMB UCL and Birkbeck and Yale University
