Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Risk of winterization cost explains unpreparedness of Texan power system during winter storm Uri
In shock we witnessed the reports about the catastrophic failure of the Texan power system in February 2021. Although based in Europe, we started immediately analyzing why Texan energy-only markets have not given the right incentives to prepare the infrastructure against such rare extreme events.
A new CRISPR/Cas9 system with high editing efficiency and fidelity
We identified a novel type II-A nuclease, FrCas9. It possesses comparable cutting efficiency to SpCas9 but with lower off-target effect. Furthermore, the specific 5'-NNTA-3' PAM enables FrCas9 to directly target the TATA-box to regulate gene expression.
Chemiluminescent screening of specific hybridoma cells via a proximity-rolling circle activated enzymatic switch
A 1-day homogeneous chemiluminescent screening protocol for specific hybridoma cells via a proximity-rolling circle activated enzymatic switch (P-RCAES) strategy has been developed. This CL assay enables the screening of specific hybridoma cells on conventional 96-well plate at single-cell level.
Omnidirectional-total-reflection metagratings: A compact strategy for guiding mechanical waves
Guidance of classical waves is key to many technologies, but high-efficiency, omnidirectional performance is difficult to achieve. Here, an ultrathin, broadband metagrating is proposed for suppression of parasitic diffraction and guiding mechanical waves along an arbitrary path.
Comments and future work for"PI3Kγ stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammation"
We have comments and plan work in the future for the work done by our lab for the paper "PI3Kγ stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammation" .
