The Impact of Toxic Effector Molecule TagX on the Amino Acid Conformation of the Hcp1 Monohexameric Ring in Acinetobacter baumannii Type VI Secretion System Utilizing Bioinformatics Tools and an AI System
This study employed machine learning and bioinformatics methods to clarify the mechanism by which Hcp1 nanotubes contract and transport effector molecules to their target cells, with A. baumannii serving as the host organism. Molecular Modeling connect Journal
RNA-Puzzles Round V: evaluation of RNA structure prediction on 23 targets
RNA-Puzzles is a community-wide evaluation of RNA 3D structure prediction since 2012. We report the state-of-the-art prediction in the field using 23 RNA targets in RNA-Puzzles Round V. See the paper: https://www.nature.com/articles/s41592-024-02543-9.
Proteomic analysis of the combined effects of cannabigerol and 3-O-ethyl ascorbic acid on kinase-dependent signalling in UVB-irradiated human keratinocytes
Phytocannabinoid CBG together with EAA, a stable, lipophilic derivative of the vitamin C, recovered human skin cells irradiated by UV light. Their effects on kinases were manifested even after 24 hours.
Effects of CBG and EAA were linked to reduced modification of keratinocyte proteins by 4-HNE.
Behind BASEPROD: Collecting a dataset for planetary exploration
The semi-desert of Bardenas Reales, Spain, offers a diverse array of terrain features ranging from rocky outcrops to sandy slopes. This is ideal for robotics researchers working on planetary exploration. We have recorded a dataset with nearly two kilometers of traverses, maps, and spectroscopy data.
Tailored pore-confined single-site iron(III) catalyst for selective CH4 oxidation to CH3OH or CH3CO2H using O2
The direct conversion of methane into methanol and acetic acid offers a sustainable pathway for producing high-value chemicals. We achieve this transformation by harnessing a multifunctional iron(III) dihydroxyl catalytic species within a MOF framework, using molecular oxygen as the oxidant.
