Hydroxylamine-Mediated C-C Amination via an Aza-Hock Rearrangement
We report the aza-Hock rearrangement of benzyl alcohols with arylsulfonyl hydroxylamines (ArSO2ONHR) in fluorinated alcohols (HFIP or TFE), delivering anilines in good to excellent yields.
Developing a hybrid process for the production of olefins from glucose using cellular and heterogeneous catalysis
In a collaboration with Paul Dauenhauer's group at the University of Minnesota through the NSF Center for Sustainable Polymers, we have developed a new strategy to deoxygenate hydrocarbons produced by microbial fermentation of glucose using simple Lewis acid catalysis.
A protein hindered from folding by its parent ribosome
Cassaignau and colleagues use NMR to reveal how a dynamic elongating nascent polypeptide interacts with the ribosome to modulate its folding (https://www.nature.com/articles/s41557-021-00796-x)
