BMC Biology is calling for submissions on our Collection on Human microbiome in health and disease. The human microbiome plays a crucial role in maintaining health. Comprising trillions of microorganisms, including bacteria, viruses, fungi, and archaea, the microbiome influences various physiological processes, such as metabolism, immune function, and even mental health through pathways like the gut-brain axis. Recent advances in sequencing technologies and bioinformatics have enabled researchers to explore the intricate relationships between the microbiome and human health, revealing its potential as a target for therapeutic interventions.

Continuing to advance our understanding of the human microbiome is essential for developing novel strategies to prevent and treat diseases. Significant progress has been made in identifying specific microbial signatures associated with conditions such as obesity, diabetes, and cancer, as well as understanding the impact of antibiotics on microbial diversity. These insights have opened new avenues for personalized medicine, where microbiome profiling could guide treatment decisions and improve patient outcomes.

As research in this field progresses, we can anticipate exciting developments, including the potential for microbiome-based therapies, such as probiotics and fecal microbiota transplantation, to become mainstream treatments. Furthermore, ongoing studies may uncover the role of the microbiome in modulating responses to immunotherapy in cancer patients, leading to more effective and tailored treatment approaches.

Potential topics for submission include, but are not limited to:

The role of the gut, oral, skin, and vaginal microbiome in health and disease

Microbial ecosystems and their impact on the immune system

The gut-brain axis: implications for mental health

The connection between the microbiome and neurodegenerative diseases

Evolution of the human microbiome across different populations

Effects of antibiotics on microbiome diversity

This Collection supports and amplifies research related to SDG 3: Good Health and Well-Being.

All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.

BMC Biology is calling for submissions to our Collection on Organoids: advancements in normal development and disease modeling, and Regenerative Medicine. This Collection seeks to bring together cutting-edge research on the use of organoids as models of normal organ development and human disease, as well as transplantable material for tissue regeneration and as a platform for drug screening.

Studies can be based on organoids derived from either induced pluripotent stem cells or tissue-derived cells (embryonic or adult stem cells or progenitor or differentiated cells from healthy or diseased tissues, such as tumors).

We welcome submissions focusing on studies investigating the mechanisms of self-organization and cellular differentiation within organoids, and how these processes recapitulate human tissue architecture and pathology. We are especially interested in studies addressing the issues of improving tissue patterning, specialization, and function, and avoiding tumorigenicity after transplantation of organoids. We will also consider studies that demonstrate the application of organoids in personalized medicine, such as drug screening, toxicity testing, and the identification of novel therapeutic targets.

We are interested in studies focusing on the refinement of methods to enhance the fidelity and functional maturity of organoids, especially those integrating organoid models with cutting-edge technologies such as advanced imaging, single-cell and spatial omics, microfluidic chip systems and bioprinting.

This Collection supports and amplifies research related to SDG 3: Good Health and Well-Being.

All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.