What is this collection about?
Tissue fibrosis, characterized by excessive accumulation of extracellular matrix components that impair organ function, contributes to a broad range of chronic diseases. Despite its significance, many of the cellular, molecular and biophysical mechanisms involved in fibrosis initiation, progression and resolution remain incompletely understood. In this cross-journal Collection, the editors of Communications Biology and Nature Communications welcome original Articles investigating fibrosis mechanisms, including fibroblast activation, fibrogenic signalling pathways, immune-stromal interactions and extracellular matrix remodelling. We also welcome translational and preclinical studies that improve understanding of fibrosis pathophysiology and support the future development of antifibrotic therapies.

Why is this collection important?
Fibrosis underlies many chronic diseases affecting diverse organs and remains a major challenge in medicine. A better understanding of the mechanisms that regulate the balance between tissue repair and excessive scarring is essential for developing new therapeutic approaches. By bringing together studies spanning cellular, molecular and translational aspects of fibrosis, this Collection aims to highlight advances that may accelerate the development of effective antifibrotic strategies and improve outcomes for patients affected by fibrotic disease.

Why submit to a collection?
Collections like this one help attract and promote high-quality science. They are led by internal In-House Editors and supported by a dedicated team of Commissioning Editors and Managing Editors at Springer Nature. Collection manuscripts typically see higher citations, downloads, and Altmetric scores, and provide a one-stop-shop on a cutting-edge topic of interest.

Who is involved?
Communications Biology is edited by both in-house professional editors and Editorial Board Members.

Nature Communications is edited by in-house professional editors.

Our editors work closely together to ensure the quality of our published papers and consistency in author experience.

How can I submit my paper?
Visit the Collection page to find out more about this collection and submit your article.