What is this collection about?
Proteins exist as flexible, dynamic ensembles sampling functionally relevant states across timescales ranging from picoseconds to seconds. Integrative experimental and computational approaches have provided insights into the functional relevance of protein dynamics, deepening understanding of protein function beyond static structures.

This joint Collection between Nature Communications, Nature Chemical Biology, Communications Biology, and Communications Chemistry welcomes primary research exploring how protein dynamics influence function, structure, and evolution. Studies may include topics such as protein interactions, protein complex organisation, and evolutionary mechanisms, using approaches such as NMR spectroscopy, cryo-electron microscopy, X-ray crystallography, molecular dynamics simulations, and single-molecule methods. Submissions are encouraged before 25 February 2027.

Why is this collection important?
Understanding protein dynamics is fundamental to decoding biological processes at the molecular level. By moving beyond static representations of proteins, researchers can uncover how conformational changes drive function, regulate interactions, and shape evolutionary pathways.

This Collection provides a platform to highlight cutting-edge advances in both experimental and computational techniques that capture these dynamic processes. Bringing together contributions across multiple journals, it aims to foster interdisciplinary collaboration and deepen insights into one of the most important challenges in Structural Biology today.

Why submit to a collection?
Collections like this one help promote high-quality science. They are led by In-House Editors who are experts in their fields and supported by a dedicated team of Commissioning Editors and Managing Editors at Springer Nature. Collection manuscripts typically see higher citations, downloads, and Altmetric scores, and provide a one-stop-shop on a cutting-edge topic of interest.

Who is involved?
Nature Communications is edited by in-house professional editors.

Nature Chemical Biology is edited by in-house professional editors.

Communications Biology is edited by both in-house professional editors and Editorial Board Members.

Communications Chemistry is edited by both in-house professional editors and Editorial Board Members.

Our editors work closely together to ensure the quality of our published papers and consistency in author experience.

How can I submit my paper?
Visit the Collection page to find out more about this collection and submit your article.