The achievement of this high impact task associated with tools and magnitudes that require to be measured must be involved in fundamental studies, proofs of concepts, prototypes and methods. Your work is welcomed to propose varied articles within multidisciplinary Research fields where Optics, Spectroscopy, Nano-Optics and Nano-spectroscopy are involved from colloids to single nanoplatforms focuses. In the context of Multifunctional materials is developed the control of the Nanoarchitecture bottom up by covalent, non-covalent bonding, polymeric support, molecular spacers and more variables to define, activate and deliver functions. Therefore, multifunctional materials with varied optical active and non-optical active properties could be delivered through 3D spaces and times. These could be part of emerging new materials with varied high impact interests such as Optoelectronics, Nanophotonics, Bioelectronics, Biophotonics, Nanomedicine, Nano-, Micro-devices, Devices, Implantables, and miniaturized instrumentations, just to mention some potential research fields. In this regard, it is currently offered a high Impact Topical collection focusing on “Discover Advances in the Design and Synthesis of Nano- Optics and Applications” (https://link.springer.com/collections/iffbffbjdg).